The effects of personal music devices on pedestrian behaviour

It has been suggested that pedestrians listening to personal music devices (PMD) are more likely to be involved in accidents than those not listening to PMDs. Though it has been demonstrated that pedestrians on cell phones exhibit less cautionary behaviour when street crossing ( [Hatfield and Murphy, 2007], [Nasar et al., 2008] and [Stavrinos et al., 2009]), little research has been conducted with PMD users. In the present study, cautionary behaviour (e.g., looking before crossing a road) was observed and recorded for pedestrians with or without PMDs. Amongst males, pedestrians listening to PMDs displayed more looking behaviour than those not listening to PMDs. Females showed no differences between the two conditions. Thus, unlike cell phones, PMDs do not decrease the cautionary behaviour of pedestrians. This suggests that cell phones and PMDs are two different types of distractions, and this needs to be taken into account when developing methods to prevent pedestrian accidents in the future.     

Aerobic oxidation of secondary benzyl alcohols catalyzed by phosphinite-based palladium pincer complexes

Environmental Chemistry Letters - Aerobic oxidation of organic compounds is receiving attention because molecular oxygen is an abundant, cheap and comparatively safe reagent. Several catalyst...     

Maternally inherited autosomal dominant PLAG-1 related Silver Russell syndrome in a fetus with intra-uterine growth restriction

We report a case of maternally inherited autosomal dominant PLAG-1 related Silver Russell syndrome (SRS) in a fetus with IUGR and a mother who had growth and feeding problems in early life, dextrocardia and an atrio-ventricular septal defect. Amniocentesis was performed due to marked intra-uterine growth restriction (IUGR). The array was normal. Whole exome sequencing (WES) revealed a maternally inherited heterozygous likely pathogenic variant in PLAG1 (NM_002655.3): c.402delT p.(Gly135Aspfs*94). This variant has not been reported previously. PLAG1 pathogenic variants are associated with autosomal dominant Silver Russell syndrome, which fits with the clinical phenotypes of both fetus and mother. PLAG1 variants have previously been reported post-natally in Silver Russell syndrome, but the phenotype tends to be milder than in 11p15.5 methylation-related cases with fewer physical features. Although cardiac anomalies are uncommon in SRS, they have been previously reported. To our knowledge, dextrocardia has not been previously associated with SRS and there were no other potential causative genetic variants found. This report aims to highlight this rare type of SRS as a cause of IUGR.